rs17115100
A SNP in the CYP17A1 gene on chromosome 10. Its most notable genotype is T;T: Increased risk of developing Parkinson's Disease
- Gene
- CYP17A1
- Location
- Chr 10102,831,636 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 16%
Genotypes
As shown in 23andMe and AncestryDNA files.
- G;GGoodcommon on affy axiom data
- G;TBadslightly increased risk of developing Parkinson's Disease
- T;TMost notableBadIncreased risk of developing Parkinson's Disease
On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 70% G;T 25% T;T 5%
- European ancestry (Utah)G;G 85% G;T 14% T;T <1%
- Han Chinese (Beijing)G;G 42% G;T 42% T;T 17%
- Japanese (Tokyo)G;G 44% G;T 43% T;T 12%
- Yoruba (Nigeria)G;G 93% G;T 7% T;T 0%
- African ancestry (Southwest US)G;G 90% G;T 11% T;T 0%
- Chinese (Denver)G;G 42% G;T 46% T;T 12%
- Gujarati IndianG;G 52% G;T 41% T;T 8%
- Luhya (Kenya)G;G 91% G;T 9% T;T 0%
- Mexican ancestry (Los Angeles)G;G 64% G;T 31% T;T 5%
- Maasai (Kenya)G;G 89% G;T 11% T;T 0%
- TuscanG;G 78% G;T 22% T;T 1%
Related
Other CYP17A1 SNPs
- rs104894135G;GComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894138A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894141T;TComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894142A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894143G;GComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894144C;CComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894145A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894146C;CComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
Source and license
Adapted from rs17115100 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.