rs174575

A SNP in the FADS2 gene on chromosome 11. Its most notable genotype is C;C.

Gene
FADS2
Location
Chr 1161,834,531 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
23%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.067% of people
  2. C;GNot ratedNo summary available.Typical · 0.029% of people
  3. G;GNot ratedNo summary available.Typical · 0.05% of people

On SNPedia: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 67% C;G 29% G;G 5%
  • European ancestry (Utah)C;C 51% C;G 45% G;G 5%
  • Han Chinese (Beijing)C;C 80% C;G 18% G;G 2%
  • Japanese (Tokyo)C;C 82% C;G 16% G;G 2%
  • Yoruba (Nigeria)C;C 54% C;G 37% G;G 10%

Other FADS2 SNPs

All FADS2 SNPs

Notes

From SNPedia

Show notes, about 150 words

rs174575, has been investigated with respect to increased intelligence in breastfed children but not yielded any clear result. *Although there was no difference in IQ linked to the SNP alone, breastfed children carrying one or two copies of rs174575(C) had a significant (6 point) increase in IQ compared to carriers of the same allele who were not breastfed. For children who were homozygous non-carriers, i.e. rs174575(G;G) individuals, there was no effect of breastfeeding on IQ. *did not replicate those findings. In contrast to their study, (G;G) children exhibited the greatest difference between feeding methods such that breastfed children performed similarly irrespective of child genotype whereas formula fed (G;G) children performed worse than other children on formula milk Expanded discussion at http://eurogene.blogspot.com/2011/06/genetic-testing-and-potential-harm-dtc.html Breastfeeding and IQ

Source and license

Adapted from rs174575 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.