rs17879961
A SNP in the CHEK2 gene on chromosome 22. Its most notable genotype is T;T.
- Gene
- CHEK2
- Location
- Chr 2228,725,099 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- <1%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs17879961 on the minus strand: (A;A), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageT;T 0% A;A 98%
- Japanese (Tokyo)T;T 0% A;A 98%
- African ancestry (Southwest US)T;T 0% A;A 97%
- Luhya (Kenya)T;T 0% A;A 99%
- Maasai (Kenya)T;T 0% A;A 99%
Related
Conditions, medicines and genes
Other CHEK2 SNPs
- rs121908702A;CBreast cancer associated mutationVery important
- rs137853007A;GBreast cancer associated mutationVery important
- rs587780183-;ABreast cancer associated mutationVery important
- rs587780184-;ABreast cancer associated mutationVery important
- rs587780186-;CBreast cancer associated mutationVery important
- rs587781269A;GBreast cancer associated mutationVery important
- rs587781592A;GBreast cancer associated mutationVery important
- rs587781699C;TBreast cancer associated mutationVery important
Notes
From SNPedia
Notes
This SNP, a variant in the CHEK2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry. For this particular SNP, the risk (minor) allele is (C). rs17879961 one of 3 SNPs associated with increased risk of lung cancer
Source and license
Adapted from rs17879961 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.