rs1799722(T;T)
Associated with endurance performance
- Magnitude
- 1.0Minor
- Repute
- Good
- Frequency
- 17%Average of 11 populations
- On SNPedia
- rs1799722(T;T)
- Gene
- BDKRB2
Frequency
Share of people with T;T in each HapMap population.
- Han Chinese (Beijing)33%
- Chinese (Denver)28%
- Japanese (Tokyo)27%
- Tuscan27%
- European ancestry (Utah)20%
- Gujarati Indian15%
- African ancestry (Southwest US)14%
- Mexican ancestry (Los Angeles)14%
- Maasai (Kenya)7%
- Luhya (Kenya)4%
- Yoruba (Nigeria)3%
Other genotypes of rs1799722
Notes
From SNPedia
In Mount Olympus marathon runners, male athletes showed a statistically significant yet slight excess of the TT genotype at rs1799722 (bradykinin B2 receptor, BDKRB2) (P=0.018; P=0.006 when limited to 316 habitual male runners) Bradykinin is a potent endothelium-dependent vasodilator, leading to a drop in blood pressure. Bradykinin dilates blood vessels by stimulating the release of prostacyclin and nitric oxide (NO). Bradykinin levels are increased by ACE inhibitors.
References
Source and license
Adapted from rs1799722(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.