rs1799864

A SNP in the CCR2 gene on chromosome 3. Its most notable genotype is A;A.

Gene
CCR2
Location
Chr 346,357,717 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
17%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodNo summary available.Typical · 0.02% of people
  2. A;GGoodNo summary available.Typical · 0.036% of people
  3. G;GGoodcommon in clinvarTypical · 0.063% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageA;A 2% A;G 36% G;G 63%
  • European ancestry (Utah)A;A 2% A;G 18% G;G 80%
  • Han Chinese (Beijing)A;A 2% A;G 44% G;G 53%
  • Japanese (Tokyo)A;A 0% A;G 51% G;G 49%
  • Yoruba (Nigeria)A;A 3% A;G 28% G;G 68%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Compared with individuals without CCR5-Delta32 (a variation in another gene) or rs1799864(A), individuals with one or two copies of rs1799864(A) had a 58% lower risk of developing AIDS during the first 4 years after testing positive for HIV, a 19% lower risk during the subsequent 4 years, and no significant protection thereafter. No protective effect (ie no benefit) was seen for this SNP once AIDS had developed. rs1799864(G), rs3025058(A) and rs662 were associated with increased risk, and rs1800775(A) with reduced risk of recurrent venous thromboembolism

Source and license

Adapted from rs1799864 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.