rs1799941

A SNP in the SHBG gene on chromosome 17. Its most notable genotype is A;A: Sex Hormone-Binding Globulin levels are 0.4 standard deviations higher

Gene
SHBG
Location
Chr 177,630,105 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedSex Hormone-Binding Globulin levels are 0.4 standard deviations higherMinor · 1.52% of people
  2. A;GNot ratedSex Hormone-Binding Globulin levels are 0.2 standard deviations higherTypical · 0.018% of people
  3. G;GNot ratedNo summary available.Typical · 0.080% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageA;A 2% A;G 18% G;G 80%
  • European ancestry (Utah)A;A 5% A;G 35% G;G 60%
  • Han Chinese (Beijing)A;A 0% A;G 2% G;G 99%
  • Yoruba (Nigeria)A;A 0% A;G 5% G;G 95%
  • African ancestry (Southwest US)A;A 2% A;G 9% G;G 90%
  • Gujarati IndianA;A 3% A;G 21% G;G 76%
  • Luhya (Kenya)A;A 0% A;G 5% G;G 96%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 26% G;G 74%
  • Maasai (Kenya)A;A <1% A;G 14% G;G 85%
  • TuscanA;A 7% A;G 43% G;G 50%

Other SHBG SNPs

All SHBG SNPs

Notes

From SNPedia

Notes

Sex Hormone Regulation

Source and license

Adapted from rs1799941 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.