rs6258
A SNP in the SHBG gene on chromosome 17. Its most notable genotype is C;C: common in complete genomics
- Gene
- SHBG
- Location
- Chr 177,631,360 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 7 HapMap populations.
- AverageC;C 99%
- European ancestry (Utah)C;C 96%
- Han Chinese (Beijing)C;C 99%
- Japanese (Tokyo)C;C 99%
- Yoruba (Nigeria)C;C 99%
- Luhya (Kenya)C;C 99%
- Mexican ancestry (Los Angeles)C;C 98%
- TuscanC;C 99%
Related
Notes
From SNPedia
Notes
testosterone levels in men. 23andMe blog See also rs12150660 Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
Source and license
Adapted from rs6258 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.