rs1800215

A SNP in the COL1A1 gene on chromosome 17. Its most notable genotype is T;T: common in clinvar

Gene
COL1A1
Location
Chr 1750,188,134 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
2%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in clinvarTypical · 0.0<1% of people
  2. G;GNot ratedNo summary available.Typical · 0.00% of people
  3. C;CGoodcommon in complete genomicsTypical · 0.094% of people

SNPedia records rs1800215 on the minus strand: (A;A), (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageT;T <1% G;G 0% C;C 94%
  • European ancestry (Utah)T;T 0% G;G 0% C;C 94%
  • Han Chinese (Beijing)T;T 0% G;G 0% C;C 100%
  • Japanese (Tokyo)T;T 0% G;G 0% C;C 100%
  • Yoruba (Nigeria)T;T 0% G;G 0% C;C 89%
  • African ancestry (Southwest US)T;T 0% G;G 0% C;C 88%
  • Chinese (Denver)T;T 0% G;G 0% C;C 99%
  • Gujarati IndianT;T 0% G;G 0% C;C 99%
  • Luhya (Kenya)T;T 0% G;G 0% C;C 89%
  • Maasai (Kenya)T;T 1% G;G 0% C;C 90%
  • TuscanT;T 0% G;G 0% C;C 96%

Other COL1A1 SNPs

All COL1A1 SNPs

Notes

From SNPedia

Notes

Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes. Mutation and polymorphism spectrum in osteogenesis imperfecta type II: implications for genotype-phenotype relationships. Connective tissue and related disorders and preterm birth: clues to genes contributing to prematurity.

Source and license

Adapted from rs1800215 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.