rs2075559
A SNP in the COL1A1 gene on chromosome 17. Its most notable genotype is G;G: common in clinvar
- Gene
- COL1A1
- Location
- Chr 1750,189,930 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 47%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2075559 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageG;G 23%
- European ancestry (Utah)G;G 24%
- Han Chinese (Beijing)G;G 29%
- Japanese (Tokyo)G;G 23%
- Yoruba (Nigeria)G;G 15%
Related
Other COL1A1 SNPs
- rs67828806C;TPossible "Oi/eds syndrome" (mild collagen disorder): Feedback WantedImportant
- rs1800012A;AComplex; possibly lower risk of ACL ruptures, yet higher risk for bone loss and disc diseaseWorth knowing
- rs1061237A;Acommon in clinvarTypical
- rs1107946C;Ccommon in complete genomicsTypical
- rs1800215T;Tcommon in clinvarTypical
- rs17639446A;Acommon in complete genomicsTypical
Source and license
Adapted from rs2075559 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.