rs1800590
A SNP in the LPL gene on chromosome 8. Its most notable genotype is T;T: common in complete genomics
- Gene
- LPL
- Location
- Chr 819,939,160 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 11%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageT;T 79%
- European ancestry (Utah)T;T 95%
- Han Chinese (Beijing)T;T 100%
- Japanese (Tokyo)T;T 100%
- Yoruba (Nigeria)T;T 20%
Related
Other LPL SNPs
- rs118204057A;AHyperlipoproteinemia, type IVery important
- rs118204059A;AHyperlipoproteinemia, type IVery important
- rs118204060T;THyperlipoproteinemia, type IVery important
- rs268G;G3X+ increased risk for venous thromboembolismWorth knowing
- rs326A;Alower HDL cholesterolWorth knowing
- rs321G;Gcommon in complete genomicsTypical
- rs325T;TNo summary available.Typical
- rs328C;Ccommon in clinvarTypical
Notes
From SNPedia
Notes
A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease. This SNP maps to a position listed in Table S6 as a non-coding variant that their biocurators felt was convincingly associated with a Mendelian disease.
Source and license
Adapted from rs1800590 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.