rs1805477

A SNP in the GRIN2B gene on chromosome 12. Its most notable genotype is C;C: common in complete genomics

Gene
GRIN2B
Location
Chr 1213,561,795 (GRCh38)
Highest magnitude
0.0Typical
Tested on
Not on consumer chips
Minor allele frequency
8%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.078% of people
  2. T;TGoodcommon in clinvarTypical · 0.04% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageC;C 78% T;T 4%
  • European ancestry (Utah)C;C 99% T;T 0%
  • Han Chinese (Beijing)C;C 100% T;T 0%
  • Japanese (Tokyo)C;C 100% T;T 0%
  • Yoruba (Nigeria)C;C 40% T;T 12%
  • African ancestry (Southwest US)C;C 53% T;T 5%
  • Luhya (Kenya)C;C 44% T;T 16%
  • Mexican ancestry (Los Angeles)C;C 98% T;T 0%
  • Maasai (Kenya)C;C 69% T;T 4%
  • TuscanC;C 99% T;T 0%

Source and license

Adapted from rs1805477 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.