rs1806201

A SNP in the GRIN2B gene on chromosome 12. Its most notable genotype is G;G: common in clinvar

Gene
GRIN2B
Location
Chr 1213,564,574 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
31%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in clinvarTypical · 0.053% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 53%
  • European ancestry (Utah)G;G 63%
  • Han Chinese (Beijing)G;G 26%
  • Japanese (Tokyo)G;G 27%
  • Yoruba (Nigeria)G;G 81%
  • African ancestry (Southwest US)G;G 72%
  • Chinese (Denver)G;G 20%
  • Gujarati IndianG;G 39%
  • Luhya (Kenya)G;G 82%
  • Mexican ancestry (Los Angeles)G;G 43%
  • Maasai (Kenya)G;G 80%
  • TuscanG;G 52%

Other GRIN2B SNPs

All GRIN2B SNPs

Notes

From SNPedia

Notes

Polymorphisms in the NMDA subunit 2B are not associated with alcohol dependence and alcohol withdrawal-induced seizures and delirium tremens. Association analysis of GRIN2B, encoding N-methyl-D-aspartate receptor 2B subunit, and Alzheimer's disease. Association between NMDA receptor subunit 2b gene polymorphism and Alzheimer's disease in Chinese Han population in Shanghai. Variations in the GRIN2B gene are associated with risky decision-making. Variation in the NMDA receptor 2B subunit gene GRIN2B is associated with differential language lateralization.

Source and license

Adapted from rs1806201 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.