rs1811399

A SNP in the NPAS2 gene on chromosome 2. Its most notable genotype is C;C.

Gene
NPAS2
Location
Chr 2100,862,552 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
28%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.010% of people
  2. A;AGoodNo summary available.Typical · 0.051% of people

SNPedia records rs1811399 on the minus strand: (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 10% A;A 51%
  • European ancestry (Utah)C;C 8% A;A 65%
  • Han Chinese (Beijing)C;C 12% A;A 47%
  • Japanese (Tokyo)C;C 10% A;A 41%
  • Yoruba (Nigeria)C;C 9% A;A 44%
  • African ancestry (Southwest US)C;C 16% A;A 49%
  • Chinese (Denver)C;C 9% A;A 46%
  • Gujarati IndianC;C 12% A;A 57%
  • Luhya (Kenya)C;C 5% A;A 52%
  • Mexican ancestry (Los Angeles)C;C 17% A;A 45%
  • Maasai (Kenya)C;C 9% A;A 48%
  • TuscanC;C 5% A;A 63%

Conditions, medicines and genes

Other NPAS2 SNPs

All NPAS2 SNPs

Notes

From SNPedia

Notes

nature The inheritance of the AC haplotype of rs1861972 – rs1861973, the C allele of rs1811399, and the C allele of rs1234747 may contribute to autism by affecting microRNA

Source and license

Adapted from rs1811399 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.