rs1834481

A SNP in the IL18 gene on chromosome 11. Its most notable genotype is C;C: common on affy axiom data

Gene
IL18
Location
Chr 11112,153,104 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
10%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon on affy axiom dataTypical · 0.087% of people

SNPedia records rs1834481 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageC;C 87%
  • European ancestry (Utah)C;C 58%
  • Han Chinese (Beijing)C;C 99%
  • Japanese (Tokyo)C;C 99%
  • Yoruba (Nigeria)C;C 100%
  • African ancestry (Southwest US)C;C 97%
  • Gujarati IndianC;C 80%
  • Mexican ancestry (Los Angeles)C;C 83%
  • Maasai (Kenya)C;C 98%
  • TuscanC;C 71%

Other IL18 SNPs

All IL18 SNPs

Notes

From SNPedia

Notes

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery. Immunogenetics of seasonal influenza vaccine response. Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.

Source and license

Adapted from rs1834481 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.