rs1864163
A SNP in the CETP gene on chromosome 16. Its most notable genotype is A;G: associated with higher HDL cholesterol
- Gene
- CETP
- Location
- Chr 1656,963,321 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 23%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableGoodassociated with higher HDL cholesterol
- G;GGoodassociated with higher HDL cholesterol
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;G 34% G;G 59%
- European ancestry (Utah)A;G 41% G;G 53%
- Han Chinese (Beijing)A;G 22% G;G 76%
- Japanese (Tokyo)A;G 21% G;G 78%
- Yoruba (Nigeria)A;G 41% G;G 52%
- African ancestry (Southwest US)A;G 42% G;G 47%
- Chinese (Denver)A;G 21% G;G 76%
- Gujarati IndianA;G 40% G;G 55%
- Luhya (Kenya)A;G 37% G;G 46%
- Mexican ancestry (Los Angeles)A;G 30% G;G 68%
- Maasai (Kenya)A;G 44% G;G 44%
- TuscanA;G 41% G;G 52%
Related
Conditions, medicines and genes
Other CETP SNPs
- rs708272A;AB2B2 genotype; some reduction in heart disease risk from moderate alcohol consumptionWorth knowing
- rs5882G;GLonger lifespan, 0.28x lower risk of dementia, 0.31x lower risk of Alzheimer's.Worth knowing
- rs5880G;Gcommon in complete genomicsTypical
- rs1532624C;Ccommon in clinvarTypical
- rs2303790A;Acommon in clinvarTypical
Notes
From SNPedia
Notes
G allele is associated with 4.12mg/dl increase in HDL cholesterol (good cholesterol).
Source and license
Adapted from rs1864163 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.