rs189840848

A SNP in the COQ6 gene on chromosome 14. Its most notable genotype is T;T: Coenzyme Q10 Deficiency; severity varies

Gene
COQ6
Location
Chr 1473,958,149 (GRCh38)
Highest magnitude
5.6Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0
  2. C;GBadCarrier of a coenzyme Q10 deficiency mutationImportant · 3.0
  3. T;TMost notableBadCoenzyme Q10 Deficiency; severity variesVery important · 5.6

On SNPedia: (C;C), (C;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other COQ6 SNPs

All COQ6 SNPs

Notes

From SNPedia

Notes

Note presence of both C>G and C>T mutations at this SNP; the C>T is reported as pathogenic, whereas the C>G is not.

C;G

Unaffected in absence of a second mutation; see coenzyme Q10 deficiency

T;T

see coenzyme Q10 deficiency

Source and license

Adapted from rs189840848 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.