rs1934341
A SNP. Its most notable genotype is C;T: Among gout patients, better response to allopurinol
- Gene
- None listed
- Highest magnitude
- 2.0Worth knowing
- Tested on
- 23andMe, FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon/normal
- C;TMost notableGoodAmong gout patients, better response to allopurinol
- T;TGoodAmong gout patients, better response to allopurinol
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs1934341 represents a variant in the GREM2 gene on chromosome 1. A 2019 publication reports that among gout patients treated with allopurinol, those carrying at least rs1934341(T) responded better, i.e. they were more likely to reduce their serum uric acid (SUA) to target levels (OR 1.35, p = 0.009).
C;T
see text of main rs-page
T;T
see text of main rs-page
Source and license
Adapted from rs1934341 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.