rs201930497

A SNP in the TCHH gene on chromosome 1. Its most notable genotype is A;A: Uncombable hair syndrome

Gene
TCHH
Location
Chr 1152,112,226 (GRCh38)
Highest magnitude
3.3Important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadUncombable hair syndromeImportant · 3.3
  2. A;GBadCarrier of an uncombable hair syndrome variantImportant · 3.0
  3. G;GGoodcommon/normalTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TCHH SNPs

All TCHH SNPs

Notes

From SNPedia

Notes

Uncombable hair syndrome variant in TCHH gene, c.991C>T or p.Gln331*

A;A

see uncombable hair syndrome

A;G

see uncombable hair syndrome; unaffected unless carrying another related mutation

Source and license

Adapted from rs201930497 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.