rs2048718
A SNP in the BRIP1 gene on chromosome 17. Its most notable genotype is C;C: common in clinvar
- Gene
- BRIP1
- Location
- Chr 1761,863,458 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 49%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 32%
- European ancestry (Utah)C;C 36%
- Han Chinese (Beijing)C;C 6%
- Japanese (Tokyo)C;C 3%
- Yoruba (Nigeria)C;C 71%
- African ancestry (Southwest US)C;C 47%
- Chinese (Denver)C;C 4%
- Gujarati IndianC;C 5%
- Luhya (Kenya)C;C 55%
- Mexican ancestry (Los Angeles)C;C 21%
- Maasai (Kenya)C;C 60%
- TuscanC;C 40%
Related
Other BRIP1 SNPs
- rs137852986A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs149364097C;GOvarian cancer susceptibilityVery important
- rs368796923A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs574552037C;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs575595017A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs587778134-;TTOvarian cancer susceptibilityVery important
- rs587780226A;GOvarian cancer susceptibilityVery important
- rs587780228A;CIncreased cancer risk; ovarian cancer & relatedVery important
Source and license
Adapted from rs2048718 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.