rs2060793

A SNP in the LOC107984314 gene on chromosome 11. Its most notable genotype is A;A: Lower serum levels of vitamin D

Gene
LOC107984314
Location
Chr 1114,893,764 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
36%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodLower serum levels of vitamin DWorth knowing · 2.014% of people
  2. G;GNot ratedHigher serum levels of vitamin DMinor · 1.040% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 14% G;G 40%
  • European ancestry (Utah)A;A 16% G;G 37%
  • Han Chinese (Beijing)A;A 12% G;G 47%
  • Japanese (Tokyo)A;A 14% G;G 40%
  • Yoruba (Nigeria)A;A 11% G;G 43%
  • African ancestry (Southwest US)A;A 18% G;G 35%
  • Chinese (Denver)A;A 14% G;G 44%
  • Gujarati IndianA;A 18% G;G 32%
  • Luhya (Kenya)A;A 14% G;G 40%
  • Mexican ancestry (Los Angeles)A;A 16% G;G 33%
  • Maasai (Kenya)A;A 11% G;G 50%
  • TuscanA;A 9% G;G 40%

Other LOC107984314 SNPs

All LOC107984314 SNPs

Notes

From SNPedia

Notes

Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study. Concluded that familial longevity was associated with a lower vitamin D levels and a lower frequency of the allelic variation in the CYP2R1 gene. Genome-wide association study of circulating vitamin D levels. This SNP is part of CYP2R1, which encodes a key C-25 hydroxylase that converts vitamin D3 to an active vitamin D receptor ligand. This SNP, along with rs2282679, rs3829251, and rs6599638 accounted for 2.8% of the variance in circulating vitamin D levels.

Source and license

Adapted from rs2060793 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.