rs2075650(G;G)

Possibly 4x higher Alzheimer's risk

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
2%Average of 11 populations
On SNPedia
rs2075650(G;G)
Gene
TOMM40

Frequency

Share of people with G;G in each HapMap population.

  • Yoruba (Nigeria)4%
  • European ancestry (Utah)4%
  • African ancestry (Southwest US)4%
  • Gujarati Indian3%
  • Chinese (Denver)2%
  • Luhya (Kenya)2%
  • Tuscan1%
  • Japanese (Tokyo)<1%
  • Han Chinese (Beijing)<1%
  • Maasai (Kenya)<1%
  • Mexican ancestry (Los Angeles)0%

Other genotypes of rs2075650

  1. A;AGoodnormal; some association with greater longevityTypical · 0.077% of people
  2. A;GMost notableBadpossibly 2x higher Alzheimer's riskWorth knowing · 2.021% of people

All about rs2075650

Notes

From SNPedia

Recent work suggests, however, that the linkage disequilibrium between rs2075650 and the ApoE ε4 defining SNP rs429358 means that there may be little, if any, independent effect of rs2075650 on Alzheimer's risk.

Source and license

Adapted from rs2075650(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.