rs2104286(C;C)

Protective minor allele, slightly reducing risk for MS & RA

Magnitude
1.4Minor
Repute
Good
Frequency
2%Average of 11 populations
On SNPedia
rs2104286(G;G)Minus strand
Gene
IL2RA

Frequency

Share of people with C;C in each HapMap population.

  • European ancestry (Utah)9%
  • Tuscan8%
  • Han Chinese (Beijing)2%
  • Gujarati Indian2%
  • Japanese (Tokyo)2%
  • African ancestry (Southwest US)2%
  • Chinese (Denver)2%
  • Yoruba (Nigeria)0%
  • Luhya (Kenya)0%
  • Mexican ancestry (Los Angeles)0%
  • Maasai (Kenya)0%

Other genotypes of rs2104286

  1. T;TBad1.7x risk for RA; 1.6X for T1D; also MS?Typical · 0.078% of people
  2. C;TBad1.4x risk for RA; 1.3x for T1D; also MS?Typical · 0.020% of people

All about rs2104286

Source and license

Adapted from rs2104286(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.