rs2146807

A SNP in the CXCL12 gene on chromosome 10. Its most notable genotype is T;T: common in complete genomics

Gene
CXCL12
Location
Chr 1044,318,290 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
16%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.065% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 65%
  • European ancestry (Utah)T;T 67%
  • Han Chinese (Beijing)T;T 79%
  • Japanese (Tokyo)T;T 80%
  • Yoruba (Nigeria)T;T 56%
  • African ancestry (Southwest US)T;T 53%
  • Chinese (Denver)T;T 88%
  • Gujarati IndianT;T 69%
  • Luhya (Kenya)T;T 49%
  • Mexican ancestry (Los Angeles)T;T 60%
  • Maasai (Kenya)T;T 53%
  • TuscanT;T 64%

Other CXCL12 SNPs

All CXCL12 SNPs

Notes

From SNPedia

Notes

rs2146807 association with the fatality of acute coronary event

Source and license

Adapted from rs2146807 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.