rs2157678

A SNP in the TRIM10 gene on chromosome 6. Its most notable genotype is G;G: common on affy axiom data

Gene
TRIM10
Location
Chr 630,161,172 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
3%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon on affy axiom dataTypical · 0.093% of people

SNPedia records rs2157678 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 93%
  • European ancestry (Utah)G;G 71%
  • Han Chinese (Beijing)G;G 100%
  • Japanese (Tokyo)G;G 100%
  • Yoruba (Nigeria)G;G 100%

Conditions, medicines and genes

Notes

From SNPedia

Notes

HLA-DQB1 8.1 haplotype is associated with significantly lower risk for type-1 diabetes *rs2157678(T) *rs3130380(A) *rs3094628(C) *rs3130352(T)

Source and license

Adapted from rs2157678 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.