rs2187668(C;T)

Somewhat increased autoimmune disorder (lupus, celiac disease) risk; 1 HLA-DRB1*0301 allele

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
15%Average of 11 populations
On SNPedia
rs2187668(A;G)Minus strand
Gene
HLA-DQA1

Frequency

Share of people with C;T in each HapMap population.

  • Mexican ancestry (Los Angeles)31%
  • Tuscan21%
  • Maasai (Kenya)19%
  • Gujarati Indian17%
  • European ancestry (Utah)16%
  • Han Chinese (Beijing)15%
  • Yoruba (Nigeria)14%
  • Luhya (Kenya)11%
  • Chinese (Denver)10%
  • Japanese (Tokyo)6%
  • African ancestry (Southwest US)5%

Other genotypes of rs2187668

  1. T;TMost notableBadAutoimmune disorder risk (lupus, celiac disease) due to 2 HLA-DRB1*0301 allelesImportant · 3.0<1% of people
  2. C;CGoodaverageTypical · 0.084% of people

All about rs2187668

Source and license

Adapted from rs2187668(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.