rs2187668(T;T)

Autoimmune disorder risk (lupus, celiac disease) due to 2 HLA-DRB1*0301 alleles

Magnitude
3.0Important
Repute
Bad
Frequency
<1%Average of 11 populations
On SNPedia
rs2187668(A;A)Minus strand
Gene
HLA-DQA1

Frequency

Share of people with T;T in each HapMap population.

  • Mexican ancestry (Los Angeles)5%
  • African ancestry (Southwest US)2%
  • Gujarati Indian1%
  • Tuscan1%
  • Yoruba (Nigeria)<1%
  • Maasai (Kenya)<1%
  • European ancestry (Utah)0%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Chinese (Denver)0%
  • Luhya (Kenya)0%

Other genotypes of rs2187668

  1. C;TBadSomewhat increased autoimmune disorder (lupus, celiac disease) risk; 1 HLA-DRB1*0301 alleleWorth knowing · 2.115% of people
  2. C;CGoodaverageTypical · 0.084% of people

All about rs2187668

Source and license

Adapted from rs2187668(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.