rs2229774(A;G)
Higher risk for anthracycline side-effects for childhood cancer patients
- Magnitude
- 3.0Important
- Repute
- Bad
- Frequency
- 13%Average of 11 populations
- On SNPedia
- rs2229774(C;T)Minus strand
- Gene
- RARG
Frequency
Share of people with A;G in each HapMap population.
- Gujarati Indian29%
- Luhya (Kenya)27%
- Maasai (Kenya)22%
- Yoruba (Nigeria)20%
- Tuscan14%
- European ancestry (Utah)13%
- Mexican ancestry (Los Angeles)7%
- African ancestry (Southwest US)5%
- Chinese (Denver)3%
- Han Chinese (Beijing)0%
- Japanese (Tokyo)0%
Other genotypes of rs2229774
Notes
From SNPedia
~5x higher risk of cardiotoxicity from anthracycline when used to treat childhood cancers; see discussion at rs2229774
Source and license
Adapted from rs2229774(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.