rs2235544(A;A)

Risk of significantly decreased T4-T3 thyroid conversion, may worsen bone loss, brain effects

Magnitude
3.0Important
Repute
Bad
Frequency
19%Average of 11 populations
On SNPedia
rs2235544(A;A)
Gene
DIO1

Frequency

Share of people with A;A in each HapMap population.

  • Mexican ancestry (Los Angeles)48%
  • Gujarati Indian35%
  • European ancestry (Utah)31%
  • Chinese (Denver)26%
  • Han Chinese (Beijing)22%
  • Tuscan15%
  • Japanese (Tokyo)12%
  • African ancestry (Southwest US)9%
  • Luhya (Kenya)4%
  • Yoruba (Nigeria)1%
  • Maasai (Kenya)1%

Other genotypes of rs2235544

  1. A;CBadRisk of decreased thyroid hormone metabolism in peripheral tissuesWorth knowing · 2.043% of people
  2. C;CNot ratedno increased risk of thyroid hormone metabolism problemsMinor · 1.039% of people

All about rs2235544

Notes

From SNPedia

see text at rs2235544

Source and license

Adapted from rs2235544(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.