rs2235544(A;C)

Risk of decreased thyroid hormone metabolism in peripheral tissues

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
43%Average of 11 populations
On SNPedia
rs2235544(A;C)
Gene
DIO1

Frequency

Share of people with A;C in each HapMap population.

  • Tuscan56%
  • Gujarati Indian54%
  • Chinese (Denver)51%
  • Japanese (Tokyo)51%
  • Han Chinese (Beijing)51%
  • European ancestry (Utah)47%
  • Mexican ancestry (Los Angeles)41%
  • Maasai (Kenya)32%
  • African ancestry (Southwest US)32%
  • Luhya (Kenya)27%
  • Yoruba (Nigeria)25%

Other genotypes of rs2235544

  1. A;AMost notableBadRisk of significantly decreased T4-T3 thyroid conversion, may worsen bone loss, brain effectsImportant · 3.019% of people
  2. C;CNot ratedno increased risk of thyroid hormone metabolism problemsMinor · 1.039% of people

All about rs2235544

Notes

From SNPedia

see text at rs2235544

Source and license

Adapted from rs2235544(A;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.