rs2245218
A SNP in the PRDM2 gene on chromosome 1. Its most notable genotype is A;A.
- Gene
- PRDM2
- Location
- Chr 113,813,331 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 17%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2245218 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageA;A 0%
- European ancestry (Utah)A;A 0%
- Han Chinese (Beijing)A;A 0%
- Japanese (Tokyo)A;A 0%
- Yoruba (Nigeria)A;A 0%
Related
Notes
From SNPedia
Notes
rs2245218 increases susceptibility to Parkinson's disease 1.67 times for carriers of the G allele Genomewide association, Parkinson disease, and PARK10. No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening. A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.
Source and license
Adapted from rs2245218 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.