rs2697962

A SNP in the PRDM2 gene on chromosome 1. Its most notable genotype is T;T: Increased risk of developing Parkinson's Disease

Gene
PRDM2
Location
Chr 113,824,497 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
16%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadIncreased risk of developing Parkinson's DiseaseWorth knowing · 2.03% of people
  2. C;TBadSlightly increased risk of developing Parkinson's DiseaseMinor · 1.529% of people
  3. G;GNot ratedNo summary available.Typical · 0.00% of people
  4. C;CGoodNormal risk of developing Parkinson's DiseaseMinor · 1.068% of people

SNPedia records rs2697962 on the minus strand: (A;A), (A;G), (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 3% C;T 29% G;G 0% C;C 68%
  • European ancestry (Utah)T;T <1% C;T 25% G;G 0% C;C 74%
  • Han Chinese (Beijing)T;T 3% C;T 28% G;G 0% C;C 69%
  • Japanese (Tokyo)T;T 8% C;T 40% G;G 0% C;C 52%
  • Yoruba (Nigeria)T;T 3% C;T 20% G;G 0% C;C 78%
  • African ancestry (Southwest US)T;T 2% C;T 18% G;G 0% C;C 80%
  • Chinese (Denver)T;T 3% C;T 31% G;G 0% C;C 66%
  • Gujarati IndianT;T 5% C;T 53% G;G 0% C;C 43%
  • Luhya (Kenya)T;T 5% C;T 22% G;G 0% C;C 74%
  • Mexican ancestry (Los Angeles)T;T 2% C;T 33% G;G 0% C;C 65%
  • Maasai (Kenya)T;T 1% C;T 27% G;G 0% C;C 72%
  • TuscanT;T 4% C;T 26% G;G 0% C;C 71%

Other PRDM2 SNPs

All PRDM2 SNPs

Notes

From SNPedia

Notes

rs2697962 is in linkage disequilibrium with a polymorphism that increases susceptibility to Parkinson's disease 1.67 times for carriers of the A allele

Source and license

Adapted from rs2697962 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.