rs2267668

A SNP in the PPARD gene on chromosome 6. Its most notable genotype is A;A.

Gene
PPARD
Location
Chr 635,410,145 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
16%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.070% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 70%
  • European ancestry (Utah)A;A 67%
  • Han Chinese (Beijing)A;A 64%
  • Japanese (Tokyo)A;A 65%
  • Yoruba (Nigeria)A;A 80%
  • African ancestry (Southwest US)A;A 77%
  • Chinese (Denver)A;A 44%
  • Gujarati IndianA;A 67%
  • Luhya (Kenya)A;A 76%
  • Mexican ancestry (Los Angeles)A;A 88%
  • Maasai (Kenya)A;A 78%
  • TuscanA;A 65%

Conditions, medicines and genes

Other PPARD SNPs

All PPARD SNPs

Notes

From SNPedia

Notes

rs1053049, rs6902123, and rs2267668 in PPARD affect Lifestyle Intervention induced changes in overall adiposity, hepatic fat storage, and relative muscle mass. Our findings provide a mechanistic explanation for the involvement of these genetic variations in the development of insulin resistance and type-2 diabetes.

Source and license

Adapted from rs2267668 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.