rs2269475(C;T)

Increased rheumatoid arthritis risk

Magnitude
0.0Typical
Repute
Bad
Frequency
21%Average of 11 populations
On SNPedia
rs2269475(A;G)Minus strand
Gene
AIF1

Frequency

Share of people with C;T in each HapMap population.

  • Japanese (Tokyo)34%
  • Han Chinese (Beijing)29%
  • European ancestry (Utah)27%
  • African ancestry (Southwest US)26%
  • Mexican ancestry (Los Angeles)22%
  • Tuscan19%
  • Chinese (Denver)17%
  • Gujarati Indian17%
  • Maasai (Kenya)16%
  • Yoruba (Nigeria)13%
  • Luhya (Kenya)11%

Other genotypes of rs2269475

  1. T;TMost notableBadincreased rheumatoid arthritis riskMinor · 1.82% of people
  2. C;CNot ratednormalTypical · 0.077% of people

All about rs2269475

Source and license

Adapted from rs2269475(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.