rs2281617(C;C)
Normal (better) response to amphetamine
- Magnitude
- 2.0Worth knowing
- Repute
- Not rated
- Frequency
- 53%Average of 11 populations
- On SNPedia
- rs2281617(C;C)
- Gene
- OPRM1
Frequency
Share of people with C;C in each HapMap population.
- Mexican ancestry (Los Angeles)74%
- Tuscan71%
- European ancestry (Utah)69%
- African ancestry (Southwest US)67%
- Maasai (Kenya)65%
- Yoruba (Nigeria)49%
- Gujarati Indian48%
- Luhya (Kenya)42%
- Chinese (Denver)38%
- Han Chinese (Beijing)33%
- Japanese (Tokyo)31%
Other genotypes of rs2281617
Notes
From SNPedia
The main finding of the study is that subjects with genotype C/C at rs2281617 scored significantly higher on Euphoria and Energy than subjects with genotypes C/T and T/T after 10 mg amphetamine, and trends were also observed with measures of Stimulation and (lower) Sedation.
Source and license
Adapted from rs2281617(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.