rs2287622(A;G)

1.7x higher risk for intrahepatic cholestasis of pregnancy

Magnitude
0.0Typical
Repute
Bad
Frequency
44%Average of 11 populations
On SNPedia
rs2287622(C;T)Minus strand
Gene
ABCB11

Frequency

Share of people with A;G in each HapMap population.

  • Yoruba (Nigeria)55%
  • Gujarati Indian54%
  • Mexican ancestry (Los Angeles)53%
  • Luhya (Kenya)46%
  • Tuscan46%
  • Maasai (Kenya)43%
  • European ancestry (Utah)42%
  • African ancestry (Southwest US)39%
  • Han Chinese (Beijing)38%
  • Chinese (Denver)34%
  • Japanese (Tokyo)33%

Other genotypes of rs2287622

  1. G;GMost notableBad2.8x higher risk for intrahepatic cholestasis of pregnancyTypical · 0.038% of people
  2. A;AGoodnormalTypical · 0.018% of people

All about rs2287622

Source and license

Adapted from rs2287622(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.