rs2287622(G;G)

2.8x higher risk for intrahepatic cholestasis of pregnancy

Magnitude
0.0Typical
Repute
Bad
Frequency
38%Average of 11 populations
On SNPedia
rs2287622(C;C)Minus strand
Gene
ABCB11

Frequency

Share of people with G;G in each HapMap population.

  • Japanese (Tokyo)61%
  • Chinese (Denver)53%
  • Han Chinese (Beijing)52%
  • European ancestry (Utah)43%
  • Tuscan42%
  • African ancestry (Southwest US)36%
  • Maasai (Kenya)31%
  • Gujarati Indian31%
  • Yoruba (Nigeria)29%
  • Luhya (Kenya)28%
  • Mexican ancestry (Los Angeles)16%

Other genotypes of rs2287622

  1. A;GBad1.7x higher risk for intrahepatic cholestasis of pregnancyTypical · 0.044% of people
  2. A;AGoodnormalTypical · 0.018% of people

All about rs2287622

Source and license

Adapted from rs2287622(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.