rs2329340

A SNP in the DDC gene on chromosome 7. Its most notable genotype is T;T: M

Gene
DDC
Location
Chr 750,552,531 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe
Minor allele frequency
35%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableBadMMinor · 1.014% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 14%
  • European ancestry (Utah)T;T 15%
  • Han Chinese (Beijing)T;T 29%
  • Japanese (Tokyo)T;T 23%
  • Yoruba (Nigeria)T;T 5%
  • African ancestry (Southwest US)T;T 5%
  • Chinese (Denver)T;T 32%
  • Gujarati IndianT;T 21%
  • Luhya (Kenya)T;T 4%
  • Mexican ancestry (Los Angeles)T;T 2%
  • Maasai (Kenya)T;T 6%
  • TuscanT;T 13%

Other DDC SNPs

All DDC SNPs

Notes

From SNPedia

Notes

a haplotype consisting of rs2329340(A), rs11974297(C), rs2044859(T) and rs11761683(G) associated with increased incidence of migraine with aura among a sample of 528 migraine patients (308 without aura, 220 with aura) and 528 sex-matched migraine-free controls Neurotransmitter systems and neurotrophic factors in autism: association study of 37 genes suggests involvement of DDC.

T;T

A four-marker haplotype in DDC was specific to migraine with Aura (rs2329340A, rs11974297C, rs2044859T, rs11761683G)

Source and license

Adapted from rs2329340 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.