rs267606978
A SNP in the PRKAG2 gene on chromosome 7. Its most notable genotype is C;G: Familial Hypertrophic Cardiomyopathy
- Gene
- PRKAG2
- Location
- Chr 7151,564,146 (GRCh38)
- Highest magnitude
- 6.2Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;GMost notableBadFamilial Hypertrophic Cardiomyopathy
- C;CGoodcommon in clinvar
SNPedia records rs267606978 on the minus strand: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other PRKAG2 SNPs
- rs28938173G;TFamilial Hypertrophic CardiomyopathyVery important
- rs121908987C;TFamilial Hypertrophic CardiomyopathyVery important
- rs121908989A;TFamilial Hypertrophic CardiomyopathyVery important
- rs121908991C;TFamilial Hypertrophic CardiomyopathyVery important
- rs267606977C;TFamilial Hypertrophic CardiomyopathyVery important
- rs267606979A;GFamilial Hypertrophic CardiomyopathyVery important
- rs587776643-;TTAFamilial Hypertrophic CardiomyopathyVery important
- rs727504392A;GFamilial Hypertrophic CardiomyopathyVery important
Notes
From SNPedia
Notes
The rare minor allele of this variant is reported to be pathogenic/likely pathogenic for familial hypertrophic cardiomyopathy (HCM), according to .
Source and license
Adapted from rs267606978 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.