rs267607577
A SNP in the LMNA gene on chromosome 1. Its most notable genotype is -;GCAC: Dilated cardiomyopathy
- Gene
- LMNA
- Location
- Chr 1156,136,363 (GRCh38)
- Highest magnitude
- 6.2Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon in clinvar
- -;GCACMost notableBadDilated cardiomyopathy
On SNPedia: (-;-), (-;GCAC). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other LMNA SNPs
- rs56699480C;TEmery-Dreifuss Muscular DystrophyVery important
- rs57207746A;GEmery-Dreifuss Muscular DystrophyVery important
- rs58048078A;TEmery-Dreifuss Muscular DystrophyVery important
- rs60934003C;TEmery-Dreifuss Muscular DystrophyVery important
- rs61046466C;TEmery-Dreifuss Muscular DystrophyVery important
- rs267607539C;GEmery-Dreifuss Muscular DystrophyVery important
- rs267607540-;GAAEmery-Dreifuss Muscular DystrophyVery important
- rs878853220G;TEmery-Dreifuss Muscular DystrophyVery important
Notes
From SNPedia
Notes
aka c.1296_1299dupGCAC and also c.1296_1299delGCACGCAC; both are annotated in ClinVar as pathogenic or likely pathogenic for cardiomyopathy
Source and license
Adapted from rs267607577 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.