rs267608012
A SNP. Its most notable genotype is A;G: Lynch syndrome (predicted)
- Gene
- None listed
- Highest magnitude
- 6.0Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodcommon/normal
- A;GMost notableBadLynch syndrome (predicted)
On SNPedia: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
aka c.2459-12A>G (in the MSH2 gene) Reported in ClinVar as a variant of uncertain significance (VUS); however, Ambry Genetics has stated (in 2019) they have concluded it is pathogenic for Lynch syndrome based on RNA/transcriptome analysis of patients.
A;G
see text on main rs-page
Source and license
Adapted from rs267608012 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.