rs272893

A SNP in the SLC22A4 gene on chromosome 5. Its most notable genotype is C;T: common in complete genomics

Gene
SLC22A4
Location
Chr 5132,327,369 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
41%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableGoodcommon in complete genomicsTypical · 0.042% of people

SNPedia records rs272893 on the minus strand: (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 42%
  • European ancestry (Utah)C;T 52%
  • Han Chinese (Beijing)C;T 48%
  • Japanese (Tokyo)C;T 37%
  • Yoruba (Nigeria)C;T 35%
  • African ancestry (Southwest US)C;T 33%
  • Chinese (Denver)C;T 52%
  • Gujarati IndianC;T 43%
  • Luhya (Kenya)C;T 33%
  • Mexican ancestry (Los Angeles)C;T 52%
  • Maasai (Kenya)C;T 39%
  • TuscanC;T 39%

Conditions, medicines and genes

Other SLC22A4 SNPs

All SLC22A4 SNPs

Notes

From SNPedia

Notes

rs272893 and rs273900 are associated with Crohn's disease (OR 2.16; 95% CI 1.21-3.59 and OR 2.40; 95% CI 1.43-4.05)

Source and license

Adapted from rs272893 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.