rs3792876

A SNP in the SLC22A4 gene on chromosome 5. Its most notable genotype is C;C.

Gene
SLC22A4
Location
Chr 5132,301,616 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
13%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.079% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 79%
  • European ancestry (Utah)C;C 82%
  • Han Chinese (Beijing)C;C 61%
  • Japanese (Tokyo)C;C 46%
  • Yoruba (Nigeria)C;C 88%
  • African ancestry (Southwest US)C;C 90%
  • Chinese (Denver)C;C 58%
  • Gujarati IndianC;C 84%
  • Luhya (Kenya)C;C 90%
  • Mexican ancestry (Los Angeles)C;C 90%
  • Maasai (Kenya)C;C 95%
  • TuscanC;C 85%

Conditions, medicines and genes

Other SLC22A4 SNPs

All SLC22A4 SNPs

Notes

From SNPedia

Show notes, about 150 words

NOTE: information for rs1050152 was accidentally entered for this SNP, rs3792876. Although the SNPs are in the same gene, the original reference does not specifically refer to rs3792876 and the degree of linkage has not been confirmed. rs1051052, a SNP in the SLC22A4 gene known as L503F, has been associated with an autoimmune disease, in this case, Crohn's disease, odds ratio = 2.1 (CI = 1.31–3.39, p = 0.002), based on a study of 203 cases and 200 controls. The risk allele is rs1050152(T). A nearby SNP in the promoter region of the SLC22A5 gene defines a haplotype along with rs3792876, with odds ratio reported as similar for either SNP or the haplotype. rs2073838 and rs3792876 replicated for rheumatoid arthritis in Japanese, but not Caucasian populations. rs3792876 failed to showed a statistically significant association with rheumatoid arthritis

Source and license

Adapted from rs3792876 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.