rs2734849
A SNP in the ANKK1 gene on chromosome 11. Its most notable genotype is A;A: common/normal
- Gene
- ANKK1
- Location
- Chr 11113,399,438 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 27%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2734849 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 65%
- European ancestry (Utah)A;A 27%
- Han Chinese (Beijing)A;A 93%
- Japanese (Tokyo)A;A 84%
- Yoruba (Nigeria)A;A 81%
- African ancestry (Southwest US)A;A 72%
- Chinese (Denver)A;A 95%
- Gujarati IndianA;A 47%
- Luhya (Kenya)A;A 77%
- Mexican ancestry (Los Angeles)A;A 47%
- Maasai (Kenya)A;A 73%
- TuscanA;A 20%
Related
Other ANKK1 SNPs
- rs1800497A;AA1/A1: Bad at avoidance of errors. 0.25x lower OCD; 0.56x lower Tardive Diskinesia; higher ADHD; 1.4x Alcohol Dependence; lower Postoperative Nausea; Increased obesity; less pleasure response; Bupropion ineffective for smoking cessation.; 2.4x risk for adenoma recurrence.Very important
- rs2734848T;Tcommon/normalTypical
- rs4938016C;Ccommon/normalTypical
- rs11604671G;Gcommon/normalTypical
Notes
From SNPedia
Notes
blog discussed in the comments see also rs1800497
Source and license
Adapted from rs2734849 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.