rs2735839(A;G)

In prostrate cancer patients, this is statistically associated with a somewhat more aggressive cancer

Magnitude
1.6Minor
Repute
Bad
Frequency
42%Average of 11 populations
On SNPedia
rs2735839(A;G)
Gene
KLK3

Frequency

Share of people with A;G in each HapMap population.

  • Chinese (Denver)52%
  • Maasai (Kenya)49%
  • Yoruba (Nigeria)48%
  • Luhya (Kenya)48%
  • Han Chinese (Beijing)46%
  • Japanese (Tokyo)44%
  • Gujarati Indian43%
  • African ancestry (Southwest US)41%
  • Mexican ancestry (Los Angeles)40%
  • Tuscan27%
  • European ancestry (Utah)22%

Other genotypes of rs2735839

  1. A;AMost notableBadin prostrate cancer patients, this is statistically associated with a somewhat more aggressive cancerMinor · 1.811% of people
  2. G;GNot ratedNo summary available.Typical · 0.047% of people

All about rs2735839

Notes

From SNPedia

Based on a He et al. 2014 Clin Can Res article, the rs2735839(A) allele is associated with more aggressive prostate cancer in general, and Gleason score 7 patients, with increased risk of being GS 4 + 3 compared to GS 3 + 4 (odds ratio 1.85, CI: 1.31–2.61).

Source and license

Adapted from rs2735839(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.