rs281864543
A SNP in the HBA2 gene on chromosome 16. Its most notable genotype is A;G: Alpha-thalassemia allele carrier
- Gene
- HBA2
- Location
- Chr 16173,007 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableBadAlpha-thalassemia allele carrier
- G;GGoodcommon/normal
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other HBA2 SNPs
- rs28928883C;Greally altered hemoglobinImportant
- rs28928878A;GAlpha Thalassemia carrierImportant
- rs28928889C;TAlpha-thalassemia allele carrierImportant
- rs33939620G;TAlpha-thalassemia allele carrierImportant
- rs33964317C;TAlpha-thalassemia allele carrierImportant
- rs33987053G;TAlpha-thalassemia allele carrierImportant
- rs34220980A;GAlpha-thalassemia allele carrierImportant
- rs34806456A;GAlpha-thalassemia allele carrierImportant
Notes
From SNPedia
Notes
A;G
See discussion at HBA2 and Alpha Thalassemia.
Source and license
Adapted from rs281864543 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.