rs2834167(A;A)

2.67x increased risk for systemic sclerosis

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
51%Average of 11 populations
On SNPedia
rs2834167(A;A)
Gene
IL10RB

Frequency

Share of people with A;A in each HapMap population.

  • Luhya (Kenya)86%
  • Yoruba (Nigeria)82%
  • African ancestry (Southwest US)77%
  • Maasai (Kenya)77%
  • Tuscan59%
  • European ancestry (Utah)53%
  • Gujarati Indian33%
  • Japanese (Tokyo)25%
  • Chinese (Denver)25%
  • Mexican ancestry (Los Angeles)21%
  • Han Chinese (Beijing)20%

Other genotypes of rs2834167

  1. A;GNot ratednormalTypical · 0.035% of people
  2. G;GNot ratednormalTypical · 0.015% of people

All about rs2834167

Notes

From SNPedia

IL-10RB rs2834167 (A/G) polymorphism is associated with the susceptibility to systemic lupus erythematosus: evidence from a study in Chinese Han population. We found that the frequency of A allele for rs2834167 in patients (44.53 %) was significantly higher than in controls (40.16 %) (χ (2) = 5.24, P = 0.022). Allele A was associated with a 1.196-fold (95 % confidence interval (CI), 1.026-1.394) greater risk for the occurrence of SLE compared with the G allele. And both genotypes AG and AA were associated with the susceptibility to SLE as compared with the GG genotype (AG versus GG, odds ratio (OR) = 1.332; 95 %CI, 1.047-1.696; AA versus GG, OR = 1.373; 95 %CI, 1.004-1.878).

References

Source and license

Adapted from rs2834167(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.