rs2854128(A;A)

G2706A+, probably MT-Haplogroup H.

Magnitude
1.0Minor
Repute
Bad
Frequency
11%Average of 4 populations
On SNPedia
rs2854128(A;A)
Gene
None listed

Frequency

Share of people with A;A in each HapMap population.

  • European ancestry (Utah)45%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Yoruba (Nigeria)0%

Other genotypes of rs2854128

  1. G;GGoodG2706A-, not MT-Haplogroup HTypical · 0.188% of people

All about rs2854128

Notes

From SNPedia

One of the 2 ancestral mitochondrial mutations needed for mitochondrial Haplogroup H. This is a non-synonymous mutation in the mitochondrial ribosome, and possibly in the neuroprotective protein humanin. Haplogroup H has been associated with increased risk of age-related neurological diseases, suggesting that this mutation (or some other) may slightly reduce the effectiveness of mitochondria or humanin.

Source and license

Adapted from rs2854128(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.