rs28897743(A;G)

Considered a causal BRCA2 breast cancer mutation

Magnitude
6.0Very important
Repute
Bad
Frequency
2%Average of 8 populations
On SNPedia
rs28897743(A;G)
Gene
BRCA2

Frequency

Share of people with A;G in each HapMap population.

  • Mexican ancestry (Los Angeles)5%
  • Japanese (Tokyo)3%
  • Han Chinese (Beijing)2%
  • Luhya (Kenya)2%
  • African ancestry (Southwest US)2%
  • Yoruba (Nigeria)1%
  • European ancestry (Utah)<1%
  • Chinese (Denver)<1%

Other genotypes of rs28897743

  1. C;GBadBRCA2 variant considered pathogenic for breast cancerVery important · 6.00% of people
  2. G;GGoodcommon in clinvarTypical · 0.098% of people
  3. G;TBadBRCA2 variant considered pathogenic for breast cancerVery important · 6.00% of people

All about rs28897743

Notes

From SNPedia

see citations at rs28897743

Source and license

Adapted from rs28897743(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.