rs28931573

A SNP in the APOA1-AS gene on chromosome 11. Its most notable genotype is A;A: homozygous for the APOA1 Milano variant

Gene
APOA1-AS
Location
Chr 11116,836,023 (GRCh38)
Highest magnitude
3.0Important
Tested on
23andMe

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;GNot ratedpositive for the APOA1 Milano variantWorth knowing · 2.0
  3. A;AMost notableNot ratedhomozygous for the APOA1 Milano variantImportant · 3.0

SNPedia records rs28931573 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

wikipedia has a fairly detailed article on this particular variant

A;A

reduced risk of cardiovascular disease

Source and license

Adapted from rs28931573 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.