rs28937900

A SNP in the FKRP gene on chromosome 19. Its most notable genotype is A;A: Limb-girdle muscular dystrophy-dystroglycanopathy

Gene
FKRP
Location
Chr 1946,756,276 (GRCh38)
Highest magnitude
5.0Very important
Tested on
23andMe, AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadLimb-girdle muscular dystrophy-dystroglycanopathyVery important · 5.0
  2. A;CBadcarrier for Limb-girdle muscular dystrophy-dystroglycanopathyImportant · 3.0
  3. C;CGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other FKRP SNPs

All FKRP SNPs

Notes

From SNPedia

Notes

rs28937900, also known as c.826C>A, p.Leu276Ile and L276I, represents a rare variant in the FKRP gene. Inherited recessively, it is considered pathogenic by multiple submitters to ClinVar for a type of Limb-girdle muscular dystrophy-dystroglycanopathy.

A;C

Unaffected in absence of another FKRP gene mutation *english *german *russian

Source and license

Adapted from rs28937900 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.